STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCOCShort coiled-coil protein. (122 aa)    
Predicted Functional Partners:
FEZ1
Fasciculation and elongation protein zeta 1.
   
 
 0.829
PROC
Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family.
      
 0.810
FEZ2
Fasciculation and elongation protein zeta 2.
   
 
 0.801
ARL1
ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family.
   
 
 0.772
PSMC5
Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.
    
   0.744
GNPNAT1
Glucosamine 6-phosphate N-acetyltransferase.
   
  
 0.635
STYX
Serine/threonine/tyrosine interacting protein.
      
 0.628
FBXW7
F-box and WD repeat domain containing 7.
      
 0.591
LOC478678
SCHIP-1 domain-containing protein.
    
   0.583
CDC16
Cell division cycle 16.
      
 0.489
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.