STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAML3Mastermind like transcriptional coactivator 3. (1098 aa)    
Predicted Functional Partners:
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
   
 0.995
NOTCH1
Notch receptor 1.
    
 0.987
NOTCH2
Notch receptor 2.
   
 0.949
NOTCH3
Notch receptor 3.
   
 0.944
EP300
E1A binding protein p300.
   
 0.904
MAML1
Mastermind like transcriptional coactivator 1.
   
 
 
0.900
CREBBP
CREB binding protein.
   
 0.875
KAT2A
Lysine acetyltransferase 2A.
     
 0.820
NOTCH4
Notch receptor 4.
    
 0.728
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
   
 
 0.670
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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