ATG5 protein (Canis lupus familiaris) - STRING interaction network

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ATG5

Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)

Predicted Functional Partners:

ATG12

0.999

ATG3

0.999

ATG16L1

0.999

ATG7

0.998

ATG16L2

0.992

GABARAPL2

0.985

WIPI2

0.981

TECPR1

0.980

GABARAP

0.978

MAP1LC3C

0.977

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG12	ATG16L1	ENSCAFP00000000294	ENSCAFP00000052433	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy related 16 like 1.	0.999
ATG12	ATG16L2	ENSCAFP00000000294	ENSCAFP00000039203	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy related 16 like 2.	0.988
ATG12	ATG3	ENSCAFP00000000294	ENSCAFP00000015447	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 3.	0.999
ATG12	ATG5	ENSCAFP00000000294	ENSCAFP00000005515	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	ATG7	ENSCAFP00000000294	ENSCAFP00000056459	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.999
ATG12	GABARAP	ENSCAFP00000000294	ENSCAFP00000023725	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	GABA type A receptor-associated protein.	0.980
ATG12	GABARAPL2	ENSCAFP00000000294	ENSCAFP00000039909	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	GABA type A receptor associated protein like 2.	0.989
ATG12	MAP1LC3C	ENSCAFP00000000294	ENSCAFP00000041897	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Microtubule associated protein 1 light chain 3 gamma.	0.981
ATG12	TECPR1	ENSCAFP00000000294	ENSCAFP00000022707	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Tectonin beta-propeller repeat containing 1.	0.876
ATG12	WIPI2	ENSCAFP00000000294	ENSCAFP00000040282	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	WD repeat domain, phosphoinositide interacting 2.	0.920
ATG16L1	ATG12	ENSCAFP00000052433	ENSCAFP00000000294	Autophagy related 16 like 1.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
ATG16L1	ATG16L2	ENSCAFP00000052433	ENSCAFP00000039203	Autophagy related 16 like 1.	Autophagy related 16 like 2.	0.948
ATG16L1	ATG3	ENSCAFP00000052433	ENSCAFP00000015447	Autophagy related 16 like 1.	Autophagy-related protein 3.	0.998
ATG16L1	ATG5	ENSCAFP00000052433	ENSCAFP00000005515	Autophagy related 16 like 1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG16L1	ATG7	ENSCAFP00000052433	ENSCAFP00000056459	Autophagy related 16 like 1.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.852
ATG16L1	GABARAP	ENSCAFP00000052433	ENSCAFP00000023725	Autophagy related 16 like 1.	GABA type A receptor-associated protein.	0.955
ATG16L1	GABARAPL2	ENSCAFP00000052433	ENSCAFP00000039909	Autophagy related 16 like 1.	GABA type A receptor associated protein like 2.	0.953
ATG16L1	MAP1LC3C	ENSCAFP00000052433	ENSCAFP00000041897	Autophagy related 16 like 1.	Microtubule associated protein 1 light chain 3 gamma.	0.965
ATG16L1	WIPI2	ENSCAFP00000052433	ENSCAFP00000040282	Autophagy related 16 like 1.	WD repeat domain, phosphoinositide interacting 2.	0.998
ATG16L2	ATG12	ENSCAFP00000039203	ENSCAFP00000000294	Autophagy related 16 like 2.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.988