STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCDH18Protocadherin 18. (1103 aa)    
Predicted Functional Partners:
NAP1L4
Nucleosome assembly protein 1 like 4; Belongs to the nucleosome assembly protein (NAP) family.
   
  
 0.579
RACGAP1
Rac GTPase activating protein 1.
   
 
 0.579
SCUBE1
Signal peptide, CUB domain and EGF like domain containing 1.
    
 
 0.488
GRIK5
Uncharacterized protein.
   
  
 0.480
CRISP2
Cysteine rich secretory protein 2; Belongs to the CRISP family.
      
 0.478
SDK2
Sidekick cell adhesion molecule 2.
    
 
 0.476
FAM222A
Family with sequence similarity 222 member A.
      
 0.451
RHBDL2
Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.
   
 
 0.437
DRAXIN
Dorsal inhibitory axon guidance protein.
      
 0.418
CDX4
Caudal type homeobox 4.
      
 0.408
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.