STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LAPTM4ALysosomal protein transmembrane 4 alpha. (225 aa)    
Predicted Functional Partners:
LAPTM4B
Lysosomal protein transmembrane 4 beta.
  
 
 
0.915
LAPTM5
Lysosomal protein transmembrane 5.
     
0.905
RNFT1
Ring finger protein, transmembrane 1.
   
  
 0.678
HVCN1
Hydrogen voltage gated channel 1.
      
 0.672
TM9SF2
Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
   
  
 0.652
LOC611979
Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
   
  
 0.640
PIGW
Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
      
 0.637
FAM118A
Family with sequence similarity 118 member A.
   
  
 0.622
RAPGEFL1
Rap guanine nucleotide exchange factor like 1.
      
 0.621
SGMS1
Sphingomyelin synthase 1.
   
  
 0.590
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.