STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPFIA3PTPRF interacting protein alpha 3. (597 aa)    
Predicted Functional Partners:
PPFIA3-2
Uncharacterized protein.
 
     0.937
PTPRD
Protein tyrosine phosphatase receptor type D.
    
 
 0.677
ERC1
ELKS/RAB6-interacting/CAST family member 1.
   
 
 0.636
PPP2CB
Serine/threonine-protein phosphatase.
    
 
 0.586
PPP2CA
Serine/threonine-protein phosphatase.
    
 
 0.586
ERC2
ELKS/RAB6-interacting/CAST family member 2.
   
 
 0.583
KIFC2
Kinesin family member C2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.552
DPYSL3
Dihydropyrimidinase like 3.
    
 
 0.532
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 
 0.517
PPP2R1A
Protein phosphatase 2 scaffold subunit Aalpha.
    
 
 0.513
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.