STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NRDCNardilysin convertase. (1227 aa)    
Predicted Functional Partners:
IDE
Insulin degrading enzyme; Belongs to the peptidase M16 family.
   
 
 0.840
TREH
Trehalase.
   
  
 0.758
DNPEP
Aspartyl aminopeptidase; Belongs to the peptidase M18 family.
   
  
 0.741
OXNAD1
Oxidoreductase NAD binding domain containing 1.
      
 0.692
ZRANB1
Zinc finger RANBP2-type containing 1.
   
   0.574
MOB1A
MOB kinase activator 1A.
    
   0.573
CCDC130
Coiled-coil domain containing 130.
      
 0.573
PSMB7
Proteasome subunit beta.
      
 0.573
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
   0.566
RFC4
Replication factor C subunit 4.
      
 0.565
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.