STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRSS37Serine protease 37. (234 aa)    
Predicted Functional Partners:
LYPD4
LY6/PLAUR domain containing 4.
   
  
 0.781
CALHM1
Calcium homeostasis modulator 1.
      
 0.761
PKD2L1
Polycystin 2 like 1, transient receptor potential cation channel.
   
  
 0.693
CFAP73
Cilia and flagella associated protein 73.
    
 
 0.653
PKD1L3
Polycystin 1 like 3, transient receptor potential channel interacting.
   
  
 0.639
CCDC42
Coiled-coil domain containing 42.
    
 
 0.637
SPACA1
Sperm acrosome associated 1.
   
  
 0.622
TDRD15
Tudor domain containing 15.
   
  
 0.620
ZNF516
Zinc finger protein 516.
    
 
 0.617
PPP1R42
Protein phosphatase 1 regulatory subunit 42.
      
 0.615
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.