STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RASIP1Ras interacting protein 1. (1137 aa)    
Predicted Functional Partners:
RAP1B
RAP1B, member of RAS oncogene family.
    
 0.968
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.950
ARHGAP29
Rho GTPase activating protein 29.
    
 0.896
RADIL
Rap associating with DIL domain.
     
 0.883
CCM2L
CCM2 like scaffold protein.
   
 
 0.747
CFD
Rho GTPase activating protein 45.
    
 0.724
SOX18
SRY-box 18.
   
  
 0.701
ISOC2
Isochorismatase domain containing 2.
      
 0.684
PPP1R18
Protein phosphatase 1 regulatory subunit 18.
    
   0.669
IZUMO2
IZUMO family member 2.
      
 0.652
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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