STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MKRN1Uncharacterized protein. (481 aa)    
Predicted Functional Partners:
TERT
Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]
    
 
 0.692
MYPOP
Myb related transcription factor, partner of profilin.
      
 0.689
NPTX1
Neuronal pentraxin 1.
    
 
 0.624
TERF2IP
TERF2 interacting protein.
      
 0.623
DDRGK1
DDRGK domain containing 1.
      
 0.620
CNNM2
Cyclin and CBS domain divalent metal cation transport mediator 2.
      
 0.591
MAGEL2
MAGE family member L2.
    
 
 0.562
EIF4E3
Eukaryotic translation initiation factor 4E family member 3; Belongs to the eukaryotic initiation factor 4E family.
    
 
 0.541
PDLIM2
PDZ and LIM domain 2.
    
 
 0.538
NOCT
Nocturnin.
      
 0.537
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.