Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRAF3IP2TRAF3 interacting protein 2. (560 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.961
TRAF5
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.950
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
    
 0.909
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.895
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.890
IL17A
Interleukin 17A.
    
 0.862
TBK1
TANK binding kinase 1.
    
 0.860
IL17RB
Interleukin 17 receptor B.
    
 0.856
IL17RC
Interleukin 17 receptor C.
    
 0.853
TRAF1
TNF receptor associated factor 1.
    
 0.815
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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