SPRY1 protein (Canis lupus familiaris) - STRING interaction network

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Score

SPRY1

Sprouty RTK signaling antagonist 1. (319 aa)

Predicted Functional Partners:

CBL

0.783

SPRY2

0.583

EGFR

0.567

GRB2

0.533

SH3KBP1

0.531

EGF

0.520

SHOC2

0.516

STXBP6

0.515

TGFA

0.511

STAM

0.503

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBL	EGF	ENSCAFP00000046273	ENSCAFP00000016954	Cbl proto-oncogene.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	0.620
CBL	EGFR	ENSCAFP00000046273	ENSCAFP00000005164	Cbl proto-oncogene.	Receptor protein-tyrosine kinase.	0.998
CBL	GRB2	ENSCAFP00000046273	ENSCAFP00000049390	Cbl proto-oncogene.	Growth factor receptor bound protein 2.	0.998
CBL	SH3KBP1	ENSCAFP00000046273	ENSCAFP00000058783	Cbl proto-oncogene.	SH3 domain containing kinase binding protein 1.	0.991
CBL	SPRY1	ENSCAFP00000046273	ENSCAFP00000005905	Cbl proto-oncogene.	Sprouty RTK signaling antagonist 1.	0.783
CBL	SPRY2	ENSCAFP00000046273	ENSCAFP00000007862	Cbl proto-oncogene.	Sprouty RTK signaling antagonist 2.	0.998
CBL	STAM	ENSCAFP00000046273	ENSCAFP00000006746	Cbl proto-oncogene.	Signal transducing adaptor molecule.	0.505
CBL	TGFA	ENSCAFP00000046273	ENSCAFP00000005001	Cbl proto-oncogene.	EGF-like domain-containing protein.	0.529
EGF	CBL	ENSCAFP00000016954	ENSCAFP00000046273	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Cbl proto-oncogene.	0.620
EGF	EGFR	ENSCAFP00000016954	ENSCAFP00000005164	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Receptor protein-tyrosine kinase.	0.999
EGF	GRB2	ENSCAFP00000016954	ENSCAFP00000049390	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Growth factor receptor bound protein 2.	0.732
EGF	SH3KBP1	ENSCAFP00000016954	ENSCAFP00000058783	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	SH3 domain containing kinase binding protein 1.	0.590
EGF	SPRY1	ENSCAFP00000016954	ENSCAFP00000005905	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Sprouty RTK signaling antagonist 1.	0.520
EGF	SPRY2	ENSCAFP00000016954	ENSCAFP00000007862	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Sprouty RTK signaling antagonist 2.	0.561
EGF	STAM	ENSCAFP00000016954	ENSCAFP00000006746	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Signal transducing adaptor molecule.	0.511
EGF	TGFA	ENSCAFP00000016954	ENSCAFP00000005001	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	EGF-like domain-containing protein.	0.946
EGFR	CBL	ENSCAFP00000005164	ENSCAFP00000046273	Receptor protein-tyrosine kinase.	Cbl proto-oncogene.	0.998
EGFR	EGF	ENSCAFP00000005164	ENSCAFP00000016954	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	0.999
EGFR	GRB2	ENSCAFP00000005164	ENSCAFP00000049390	Receptor protein-tyrosine kinase.	Growth factor receptor bound protein 2.	0.999
EGFR	SH3KBP1	ENSCAFP00000005164	ENSCAFP00000058783	Receptor protein-tyrosine kinase.	SH3 domain containing kinase binding protein 1.	0.887