STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTPAPMitochondrial poly(A) polymerase. (584 aa)    
Predicted Functional Partners:
CALCOCO2
Calcium binding and coiled-coil domain 2.
    
 
 0.830
GRSF1
G-rich RNA sequence binding factor 1.
    
 
 0.734
LRPPRC
Leucine rich pentatricopeptide repeat containing.
   
  
 0.703
PAPOLG
Poly(A) polymerase gamma.
   
  
 0.699
PNPO
Pyridoxamine 5'-phosphate oxidase.
      
 0.640
ENSCAFP00000040194
annotation not available
      
 0.591
HECTD1
HECT domain E3 ubiquitin protein ligase 1.
   
   0.580
DYNLL2
Dynein light chain.
    
   0.567
TUFM
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
      
 0.555
PAPOLA
Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.
   
  
 0.538
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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