STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP12Poly(ADP-ribose) polymerase family member 12. (703 aa)    
Predicted Functional Partners:
RNF114
Ring finger protein 114.
    
   0.828
NUDCD1
NudC domain containing 1.
    
 
 0.769
MKRN2
Makorin ring finger protein 2.
    
 
 0.754
ISG15
ISG15 ubiquitin like modifier.
   
 
 0.704
LAD1
Ladinin 1.
      
 0.694
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductase.
      
 0.692
PROKR1
Prokineticin receptor 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.692
ZC3HAV1
Zinc finger CCCH-type containing, antiviral 1.
   
 
 0.672
PARP3
Poly [ADP-ribose] polymerase.
    
 
 0.668
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 
 0.661
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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