STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYPL1Synaptophysin like 1. (217 aa)    
Predicted Functional Partners:
VAMP2
V-SNARE coiled-coil homology domain-containing protein.
   
 
 0.814
VAMP1
Vesicle associated membrane protein 1.
   
 
 0.651
LSAMP
Limbic system associated membrane protein.
   
 
 0.631
KIF1A
Kinesin family member 1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.629
NFASC
Neurofascin.
   
 
 0.626
TDRD7
Tudor domain-containing protein 7; Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis (By similarity).
      
 0.610
LOC102151505
PH domain-containing protein.
      
 0.610
LGSN
Lengsin; May act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens. Does not seem to have enzymatic activity (By similarity); Belongs to the glutamine synthetase family.
      
 0.610
BASP1
Brain abundant membrane attached signal protein 1.
      
 0.596
GNE
Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase.
     
 0.594
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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