STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDHR3Cadherin related family member 3. (887 aa)    
Predicted Functional Partners:
GSDMB
Gasdermin domain-containing protein.
      
 0.595
ORMDL3
ORM1-like protein; Negative regulator of sphingolipid synthesis.
   
  
 0.595
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
    
 
 0.563
EFNB2
Ephrin B2; Belongs to the ephrin family.
      
 0.563
LDLRAD1
Low density lipoprotein receptor class A domain containing 1.
   
 
 0.544
CLDN17
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
  
 0.543
GPR22
G protein-coupled receptor 22.
      
 0.543
TXLNB
Taxilin beta.
      
 0.539
VPS9D1
VPS9 domain containing 1.
      
 0.527
TMEM182
Transmembrane protein 182.
      
 0.520
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.