STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EMP3Epithelial membrane protein 3; Probably involved in cell proliferation and cell-cell interactions; Belongs to the PMP-22/EMP/MP20 family. (163 aa)    
Predicted Functional Partners:
MAN1A2
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
      
 0.674
FAM83E
Family with sequence similarity 83 member E.
  
   
 0.657
FAM133B-2
Family with sequence similarity 133 member B.
      
 0.646
FAM133B
Family with sequence similarity 133 member B.
      
 0.646
ZKSCAN8
Zinc finger with KRAB and SCAN domains 8.
      
 0.634
ZBTB41
Zinc finger and BTB domain containing 41.
      
 0.613
SACS
Sacsin molecular chaperone.
   
  
 0.609
SHC2
Uncharacterized protein.
      
 0.601
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
      
 0.584
TTLL11
Tubulin tyrosine ligase like 11.
      
 0.582
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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