CNTN5 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CNTN5

Contactin 5. (1100 aa)

Predicted Functional Partners:

PTPRG

0.840

APP

0.783

PTPRZ1

0.594

NFASC

0.583

NRCAM

0.576

CHL1

0.576

L1CAM

0.575

KIRREL3

0.541

CD177

0.524

F1PSE5_CANLF

0.523

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	CNTN5	ENSCAFP00000012583	ENSCAFP00000005990	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Contactin 5.	0.783
APP	L1CAM	ENSCAFP00000012583	ENSCAFP00000061242	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	L1 cell adhesion molecule.	0.436
CD177	CNTN5	ENSCAFP00000007099	ENSCAFP00000005990	CD177 molecule.	Contactin 5.	0.524
CHL1	CNTN5	ENSCAFP00000009401	ENSCAFP00000005990	Cell adhesion molecule L1 like.	Contactin 5.	0.576
CHL1	F1PSE5_CANLF	ENSCAFP00000009401	ENSCAFP00000003148	Cell adhesion molecule L1 like.	LAM_G_DOMAIN domain-containing protein.	0.506
CHL1	L1CAM	ENSCAFP00000009401	ENSCAFP00000061242	Cell adhesion molecule L1 like.	L1 cell adhesion molecule.	0.507
CHL1	PTPRG	ENSCAFP00000009401	ENSCAFP00000056443	Cell adhesion molecule L1 like.	Protein tyrosine phosphatase receptor type G.	0.509
CNTN5	APP	ENSCAFP00000005990	ENSCAFP00000012583	Contactin 5.	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.783
CNTN5	CD177	ENSCAFP00000005990	ENSCAFP00000007099	Contactin 5.	CD177 molecule.	0.524
CNTN5	CHL1	ENSCAFP00000005990	ENSCAFP00000009401	Contactin 5.	Cell adhesion molecule L1 like.	0.576
CNTN5	F1PSE5_CANLF	ENSCAFP00000005990	ENSCAFP00000003148	Contactin 5.	LAM_G_DOMAIN domain-containing protein.	0.523
CNTN5	KIRREL3	ENSCAFP00000005990	ENSCAFP00000059630	Contactin 5.	Kirre like nephrin family adhesion molecule 3.	0.541
CNTN5	L1CAM	ENSCAFP00000005990	ENSCAFP00000061242	Contactin 5.	L1 cell adhesion molecule.	0.575
CNTN5	NFASC	ENSCAFP00000005990	ENSCAFP00000035876	Contactin 5.	Neurofascin.	0.583
CNTN5	NRCAM	ENSCAFP00000005990	ENSCAFP00000005590	Contactin 5.	Neuronal cell adhesion molecule.	0.576
CNTN5	PTPRG	ENSCAFP00000005990	ENSCAFP00000056443	Contactin 5.	Protein tyrosine phosphatase receptor type G.	0.840
CNTN5	PTPRZ1	ENSCAFP00000005990	ENSCAFP00000038572	Contactin 5.	Protein tyrosine phosphatase receptor type Z1.	0.594
F1PSE5_CANLF	CHL1	ENSCAFP00000003148	ENSCAFP00000009401	LAM_G_DOMAIN domain-containing protein.	Cell adhesion molecule L1 like.	0.506
F1PSE5_CANLF	CNTN5	ENSCAFP00000003148	ENSCAFP00000005990	LAM_G_DOMAIN domain-containing protein.	Contactin 5.	0.523
F1PSE5_CANLF	L1CAM	ENSCAFP00000003148	ENSCAFP00000061242	LAM_G_DOMAIN domain-containing protein.	L1 cell adhesion molecule.	0.506