STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC114Coiled-coil domain containing 114. (735 aa)    
Predicted Functional Partners:
CCDC151
Coiled-coil domain containing 151.
   
 0.961
EFCAB1
EF-hand calcium binding domain 1.
    
 
 0.937
CCDC39
Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.
   
 
 0.937
ARMC4
Uncharacterized protein.
   
 
 0.936
TTC25
Tetratricopeptide repeat domain 25.
   
 
 0.934
DNAI2
Dynein axonemal intermediate chain 2.
    
 
 0.915
CFAP52
Cilia and flagella associated protein 52.
   
 
 0.888
DNAI1
Dynein axonemal intermediate chain 1.
   
 
 0.885
GAA
Glucosidase alpha, acid.
   
 
 0.874
RIBC2
RIB43A domain with coiled-coils 2.
   
 
 0.861
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.