STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAML2Mastermind like transcriptional coactivator 2. (1124 aa)    
Predicted Functional Partners:
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
   
 0.996
NOTCH4
Notch receptor 4.
    
 0.986
NOTCH1
Notch receptor 1.
    
 0.975
NOTCH3
Notch receptor 3.
    
 0.972
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
   
 0.961
NOTCH2
Notch receptor 2.
    
 0.951
CREBBP
CREB binding protein.
    
 0.947
KAT2A
Lysine acetyltransferase 2A.
     
 0.940
MAML1
Mastermind like transcriptional coactivator 1.
    
 0.906
EP300
E1A binding protein p300.
    
 0.905
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.