STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CYP4X1Cytochrome P450 family 4 subfamily X member 1; Belongs to the cytochrome P450 family. (507 aa)    
Predicted Functional Partners:
SUOX
Sulfite oxidase.
     
 0.690
LYPD3
LY6/PLAUR domain containing 3.
      
 0.591
PLA2G1B
Phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules; Belongs to the phospholipase A2 family.
   
 
 0.559
SLC5A9
Solute carrier family 5 member 9; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.541
EPHX2
Epoxide hydrolase 2.
   
 0.529
CYP7A1
Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family.
  
  
 0.526
OSGIN1
Oxidative stress induced growth inhibitor 1.
    
 0.513
CYP20A1
Cytochrome P450 family 20 subfamily A member 1.
  
 0.508
AASDH
Aminoadipate-semialdehyde dehydrogenase.
  
 0.488
CYP2W1
Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family.
  
   
0.438
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.