STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIAA1549KIAA1549. (1940 aa)    
Predicted Functional Partners:
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 
 0.712
TMC3
Transmembrane channel-like protein.
    
 
 0.607
KLHDC7A
Kelch domain containing 7A.
  
   
 0.600
POMGNT1
Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-).
      
 0.523
POMT2
Protein O-mannosyltransferase 2.
      
 0.515
FAM131B
Family with sequence similarity 131 member B.
      
 0.495
POMT1
Protein O-mannosyltransferase 1.
      
 0.493
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3.
   
  
 0.490
USH2A
Usherin.
      
 0.448
NF1
Neurofibromin 1.
      
 0.440
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.