GATA2 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

GATA2

GATA binding protein 2. (480 aa)

Predicted Functional Partners:

TAL1

0.809

LMO2

0.718

FOXC2

0.709

LDB1

0.669

ZFPM2

0.662

RUNX1

0.619

NFYB

0.616

CEBPB

0.607

KLF1

0.600

LYL1

0.599

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEBPB	GATA2	ENSCAFP00000036854	ENSCAFP00000006152	CCAAT/enhancer-binding protein.	GATA binding protein 2.	0.607
CEBPB	RUNX1	ENSCAFP00000036854	ENSCAFP00000014111	CCAAT/enhancer-binding protein.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.677
FOXC2	GATA2	ENSCAFP00000029498	ENSCAFP00000006152	Forkhead box C2.	GATA binding protein 2.	0.709
GATA2	CEBPB	ENSCAFP00000006152	ENSCAFP00000036854	GATA binding protein 2.	CCAAT/enhancer-binding protein.	0.607
GATA2	FOXC2	ENSCAFP00000006152	ENSCAFP00000029498	GATA binding protein 2.	Forkhead box C2.	0.709
GATA2	KLF1	ENSCAFP00000006152	ENSCAFP00000025201	GATA binding protein 2.	Kruppel like factor 1.	0.600
GATA2	LDB1	ENSCAFP00000006152	ENSCAFP00000014734	GATA binding protein 2.	LIM domain binding 1.	0.669
GATA2	LMO2	ENSCAFP00000006152	ENSCAFP00000010588	GATA binding protein 2.	LIM domain only 2.	0.718
GATA2	LYL1	ENSCAFP00000006152	ENSCAFP00000059898	GATA binding protein 2.	Uncharacterized protein.	0.599
GATA2	NFYB	ENSCAFP00000006152	ENSCAFP00000041763	GATA binding protein 2.	Nuclear transcription factor Y subunit beta.	0.616
GATA2	RUNX1	ENSCAFP00000006152	ENSCAFP00000014111	GATA binding protein 2.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.619
GATA2	TAL1	ENSCAFP00000006152	ENSCAFP00000005977	GATA binding protein 2.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.809
GATA2	ZFPM2	ENSCAFP00000006152	ENSCAFP00000044423	GATA binding protein 2.	Zinc finger protein, FOG family member 2.	0.662
KLF1	GATA2	ENSCAFP00000025201	ENSCAFP00000006152	Kruppel like factor 1.	GATA binding protein 2.	0.600
KLF1	LDB1	ENSCAFP00000025201	ENSCAFP00000014734	Kruppel like factor 1.	LIM domain binding 1.	0.537
KLF1	LMO2	ENSCAFP00000025201	ENSCAFP00000010588	Kruppel like factor 1.	LIM domain only 2.	0.525
KLF1	LYL1	ENSCAFP00000025201	ENSCAFP00000059898	Kruppel like factor 1.	Uncharacterized protein.	0.436
KLF1	TAL1	ENSCAFP00000025201	ENSCAFP00000005977	Kruppel like factor 1.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.602
LDB1	GATA2	ENSCAFP00000014734	ENSCAFP00000006152	LIM domain binding 1.	GATA binding protein 2.	0.669
LDB1	KLF1	ENSCAFP00000014734	ENSCAFP00000025201	LIM domain binding 1.	Kruppel like factor 1.	0.537