STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NDNFNeuron derived neurotrophic factor. (568 aa)    
Predicted Functional Partners:
EGFL6
EGF like domain multiple 6.
      
 0.652
THEM5
Thioesterase superfamily member 5.
      
 0.595
ACSBG1
Acyl-CoA synthetase bubblegum family member 1.
      
 0.592
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
      
 0.591
LAMP5
Lysosomal associated membrane protein family member 5.
      
 0.580
ACOT4
Acyl-CoA thioesterase 6.
      
 0.534
ENPP2
Ectonucleotide pyrophosphatase/phosphodiesterase 2.
   
  
 0.531
CDO1
Cysteine dioxygenase.
      
 0.512
J9NRU7_CANLF
Uncharacterized protein.
      
 0.486
RELN
Reelin.
      
 0.485
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.