STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMER3APC membrane recruitment protein 3. (801 aa)    
Predicted Functional Partners:
APC
APC regulator of WNT signaling pathway.
   
   0.776
LRIG3
Leucine rich repeats and immunoglobulin like domains 3.
      
 0.756
TRABD2B
TraB domain containing 2B.
      
 0.748
SHISA3
Shisa family member 3.
      
 0.700
GFRA2
GDNF family receptor alpha 2.
      
 0.620
ANGPTL7
Angiopoietin like 7.
      
 0.605
J9P2Z7_CANLF
Uncharacterized protein.
      
 0.601
XYLT1
Xylosyltransferase 1; Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D- xylose from UDP-D-xylose to specific serine residues of the core protein. Required for normal maturation of chondrocytes during bone development, normal onset of ossification and normal embryonic and postnatal skeleton development, especially of the long bones.
      
 0.591
APC2
APC regulator of WNT signaling pathway 2.
   
   0.538
FAM180A
Family with sequence similarity 180 member A.
      
 0.533
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.