STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAREM2GRB2 associated regulator of MAPK1 subtype 2. (884 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
   
 
 0.858
GAREM1
GRB2 associated regulator of MAPK1 subtype 1.
    
   0.703
EHBP1
EH domain binding protein 1.
    
 0.600
RABIF
RAB interacting factor.
    
 
 0.567
RUBCN
Rubicon autophagy regulator.
    
  0.534
RILPL2
Rab interacting lysosomal protein like 2.
   
 
 0.530
RAB14
RAB14, member RAS oncogene family.
   
 0.528
EHBP1L1
EH domain binding protein 1 like 1.
    
 0.528
VPS16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
    
 0.517
GRAP2
GRB2 related adaptor protein 2.
   
   0.514
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.