| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABHD12 | ABHD6 | ENSCAFP00000006539 | ENSCAFP00000010991 | Abhydrolase domain containing 12. | Abhydrolase domain containing 6. | 0.953 |
| ABHD12 | DAGLB | ENSCAFP00000006539 | ENSCAFP00000023124 | Abhydrolase domain containing 12. | Diacylglycerol lipase beta. | 0.674 |
| ABHD12 | FAAH | ENSCAFP00000006539 | ENSCAFP00000006320 | Abhydrolase domain containing 12. | Fatty acid amide hydrolase. | 0.860 |
| ABHD12 | GPR55 | ENSCAFP00000006539 | ENSCAFP00000047719 | Abhydrolase domain containing 12. | G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. | 0.421 |
| ABHD12 | NAPEPLD | ENSCAFP00000006539 | ENSCAFP00000006303 | Abhydrolase domain containing 12. | N-acyl phosphatidylethanolamine phospholipase D. | 0.746 |
| ABHD6 | ABHD12 | ENSCAFP00000010991 | ENSCAFP00000006539 | Abhydrolase domain containing 6. | Abhydrolase domain containing 12. | 0.953 |
| ABHD6 | CNR1 | ENSCAFP00000010991 | ENSCAFP00000004587 | Abhydrolase domain containing 6. | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | 0.431 |
| ABHD6 | DAGLB | ENSCAFP00000010991 | ENSCAFP00000023124 | Abhydrolase domain containing 6. | Diacylglycerol lipase beta. | 0.692 |
| ABHD6 | FAAH | ENSCAFP00000010991 | ENSCAFP00000006320 | Abhydrolase domain containing 6. | Fatty acid amide hydrolase. | 0.943 |
| ABHD6 | GPR55 | ENSCAFP00000010991 | ENSCAFP00000047719 | Abhydrolase domain containing 6. | G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. | 0.569 |
| ABHD6 | NAPEPLD | ENSCAFP00000010991 | ENSCAFP00000006303 | Abhydrolase domain containing 6. | N-acyl phosphatidylethanolamine phospholipase D. | 0.872 |
| ABHD6 | TRPV1 | ENSCAFP00000010991 | ENSCAFP00000028568 | Abhydrolase domain containing 6. | Transient receptor potential cation channel subfamily V member 1; Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits [...] | 0.476 |
| CNR1 | ABHD6 | ENSCAFP00000004587 | ENSCAFP00000010991 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Abhydrolase domain containing 6. | 0.431 |
| CNR1 | DAGLB | ENSCAFP00000004587 | ENSCAFP00000023124 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Diacylglycerol lipase beta. | 0.403 |
| CNR1 | FAAH | ENSCAFP00000004587 | ENSCAFP00000006320 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Fatty acid amide hydrolase. | 0.821 |
| CNR1 | GPR55 | ENSCAFP00000004587 | ENSCAFP00000047719 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. | 0.704 |
| CNR1 | NAPEPLD | ENSCAFP00000004587 | ENSCAFP00000006303 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | N-acyl phosphatidylethanolamine phospholipase D. | 0.609 |
| CNR1 | TRPV1 | ENSCAFP00000004587 | ENSCAFP00000028568 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Transient receptor potential cation channel subfamily V member 1; Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits [...] | 0.617 |
| DAGLB | ABHD12 | ENSCAFP00000023124 | ENSCAFP00000006539 | Diacylglycerol lipase beta. | Abhydrolase domain containing 12. | 0.674 |
| DAGLB | ABHD6 | ENSCAFP00000023124 | ENSCAFP00000010991 | Diacylglycerol lipase beta. | Abhydrolase domain containing 6. | 0.692 |