LRRC41 protein (Canis lupus familiaris) - STRING interaction network

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Score

LRRC41

Leucine rich repeat containing 41. (814 aa)

Predicted Functional Partners:

RHOBTB3

0.665

CUL5

0.617

RNF7

0.601

CUL2

0.541

RBX1

0.529

ASB2

0.522

ARMT1

0.515

COMMD4

0.508

CAND1

0.506

COMMD1

0.506

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARMT1	LRRC41	ENSCAFP00000000618	ENSCAFP00000006338	Acidic residue methyltransferase 1.	Leucine rich repeat containing 41.	0.515
ASB2	CAND1	ENSCAFP00000025970	ENSCAFP00000000584	Ankyrin repeat and SOCS box containing 2.	Cullin associated and neddylation dissociated 1.	0.587
ASB2	COMMD1	ENSCAFP00000025970	ENSCAFP00000004595	Ankyrin repeat and SOCS box containing 2.	COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...]	0.531
ASB2	COMMD4	ENSCAFP00000025970	ENSCAFP00000061690	Ankyrin repeat and SOCS box containing 2.	COMM domain containing 4.	0.531
ASB2	CUL2	ENSCAFP00000025970	ENSCAFP00000061672	Ankyrin repeat and SOCS box containing 2.	Cullin 2; Belongs to the cullin family.	0.501
ASB2	CUL5	ENSCAFP00000025970	ENSCAFP00000060384	Ankyrin repeat and SOCS box containing 2.	Cullin 5; Belongs to the cullin family.	0.898
ASB2	LRRC41	ENSCAFP00000025970	ENSCAFP00000006338	Ankyrin repeat and SOCS box containing 2.	Leucine rich repeat containing 41.	0.522
ASB2	RBX1	ENSCAFP00000025970	ENSCAFP00000051832	Ankyrin repeat and SOCS box containing 2.	Ring-box 1.	0.443
ASB2	RNF7	ENSCAFP00000025970	ENSCAFP00000011412	Ankyrin repeat and SOCS box containing 2.	Ring finger protein 7.	0.695
CAND1	ASB2	ENSCAFP00000000584	ENSCAFP00000025970	Cullin associated and neddylation dissociated 1.	Ankyrin repeat and SOCS box containing 2.	0.587
CAND1	COMMD1	ENSCAFP00000000584	ENSCAFP00000004595	Cullin associated and neddylation dissociated 1.	COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...]	0.499
CAND1	COMMD4	ENSCAFP00000000584	ENSCAFP00000061690	Cullin associated and neddylation dissociated 1.	COMM domain containing 4.	0.543
CAND1	CUL2	ENSCAFP00000000584	ENSCAFP00000061672	Cullin associated and neddylation dissociated 1.	Cullin 2; Belongs to the cullin family.	0.862
CAND1	CUL5	ENSCAFP00000000584	ENSCAFP00000060384	Cullin associated and neddylation dissociated 1.	Cullin 5; Belongs to the cullin family.	0.795
CAND1	LRRC41	ENSCAFP00000000584	ENSCAFP00000006338	Cullin associated and neddylation dissociated 1.	Leucine rich repeat containing 41.	0.506
CAND1	RBX1	ENSCAFP00000000584	ENSCAFP00000051832	Cullin associated and neddylation dissociated 1.	Ring-box 1.	0.905
CAND1	RNF7	ENSCAFP00000000584	ENSCAFP00000011412	Cullin associated and neddylation dissociated 1.	Ring finger protein 7.	0.790
COMMD1	ASB2	ENSCAFP00000004595	ENSCAFP00000025970	COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...]	Ankyrin repeat and SOCS box containing 2.	0.531
COMMD1	CAND1	ENSCAFP00000004595	ENSCAFP00000000584	COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...]	Cullin associated and neddylation dissociated 1.	0.499
COMMD1	COMMD4	ENSCAFP00000004595	ENSCAFP00000061690	COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...]	COMM domain containing 4.	0.908