STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAD54LRAD54 like. (747 aa)    
Predicted Functional Partners:
RAD54B
RAD54 homolog B.
  
 
0.955
RAD51
DNA repair protein RAD51 homolog 1; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Part of a PALB2-scaffolded HR [...]
   
 
 0.946
VAC14
VAC14 component of PIKFYVE complex.
 
 
   0.901
PKMYT1
Protein kinase, membrane associated tyrosine/threonine 1.
   
 
 0.848
SAC3D1
SAC3 domain containing 1.
   
 
 0.796
RAD51B
RAD51 paralog B.
   
 
 0.779
WRN
WRN RecQ like helicase.
  
 
 0.766
FANCM
FA complementation group M.
   
 
 0.751
EXO1
Exonuclease 1.
   
 
 0.744
NFYC
Nuclear transcription factor Y subunit gamma.
   
 
 0.731
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.