Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM185AFamily with sequence similarity 185 member A. (374 aa)    
Predicted Functional Partners:
FBXL13
F-box and leucine rich repeat protein 13.
      
 0.852
NOL4
Nucleolar protein 4.
      
 0.815
APH1A
Aph-1 homolog A, gamma-secretase subunit.
      
 0.810
PEX5
Peroxisomal biogenesis factor 5.
   
 0.775
PEX5L
Peroxisomal biogenesis factor 5 like.
   
 0.775
SEMA7A
Semaphorin 7A; Belongs to the semaphorin family.
    
   0.768
LOC111097709
Uncharacterized protein.
    
   0.767
PEX19
Peroxisomal biogenesis factor 19.
   
 
 0.766
PEX7
Peroxisomal biogenesis factor 7.
    
 
 0.758
PEX12
Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.
    
 
 0.758
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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