STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMMECR1LAMMECR1 like. (310 aa)    
Predicted Functional Partners:
PDZD11
PDZ domain containing 11.
    
 
 0.515
SH3BGRL
SH3 domain binding glutamate rich protein like.
   
  
 0.505
MEMO1
Mediator of cell motility 1.
  
    0.494
AIFM1
Apoptosis inducing factor mitochondria associated 1.
   
  
 0.468
SLC4A1AP
Solute carrier family 4 member 1 adaptor protein.
   
  
 0.464
EDC3
Enhancer of mRNA decapping 3.
   
  
 0.446
EIF1AX
Eukaryotic translation initiation factor 1A X-linked; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
     
 0.446
NAXE
NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
   
  
 0.436
LOC492092
RRM domain-containing protein.
   
  
 0.417
AKAP17A
Uncharacterized protein.
      
 0.414
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.