STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CST7Cystatin F. (144 aa)    
Predicted Functional Partners:
CLEC1A
C-type lectin domain containing 7A.
      
 0.724
MATN2
Matrilin 2.
      
 0.717
TREM2
Triggering receptor expressed on myeloid cells 2.
      
 0.663
GZF1
GDNF inducible zinc finger protein 1.
      
 0.646
TNFSF11
TNF superfamily member 11; Belongs to the tumor necrosis factor family.
   
  
 0.631
P2RY12
Purinergic receptor P2Y12.
      
 0.578
ACSS1
Acetyl-coenzyme A synthetase.
   
  
 0.558
CSTL1
Cystatin like 1.
      
0.555
CTSD
Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family.
   
  
 0.553
CTSC
Dipeptidyl peptidase 1 exclusion domain chain; Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase (By similarity).
   
 
 0.537
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.