STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB43RAB43, member RAS oncogene family. (212 aa)    
Predicted Functional Partners:
USP6NL
USP6 N-terminal like.
    
 0.731
STX6
Syntaxin 6; Belongs to the syntaxin family.
    
 0.717
RABGGTB
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
    
 0.628
VAMP4
Vesicle associated membrane protein 4.
   
 
 0.622
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
 0.607
RIC1
RIC1 homolog, RAB6A GEF complex partner 1.
    
 0.606
RABGGTA
Rab geranylgeranyltransferase subunit alpha.
    
 0.606
TRAPPC1
Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.
    
 
 0.606
CHM
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.599
CBY2
Component of oligomeric golgi complex 3.
   
 0.597
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.