STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DRC1Selenoprotein I. (723 aa)    
Predicted Functional Partners:
CCDC65
Coiled-coil domain containing 65.
  
0.965
DRC7
Dynein regulatory complex subunit 7.
   
 
 0.897
DNAI2
Dynein axonemal intermediate chain 2.
   
 0.876
GAS8
Growth arrest specific 8.
  
 
 0.876
DRC3
Dynein regulatory complex subunit 3.
   
 
 0.873
CCDC39
Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.
   
 
 0.873
DNAH2
Dynein axonemal heavy chain 2.
  
 0.866
RSPH1
Radial spoke head 1 homolog.
   
 
 0.864
GAA
Glucosidase alpha, acid.
   
 
 0.860
RSPH3
Radial spoke head 3.
  
 
 0.844
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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