FOXA3 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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[Homology]

Score

FOXA3

Forkhead box A3. (350 aa)

Predicted Functional Partners:

SPDEF

0.785

FOXA1

0.627

MYL7

0.581

GATA4

0.576

LGALS2

0.555

HHEX

0.549

OCIAD2

0.533

CLCA1

0.522

GATA1

0.518

FOXA2

0.513

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLCA1	FOXA3	ENSCAFP00000030036	ENSCAFP00000006480	Chloride channel accessory 1.	Forkhead box A3.	0.522
CLCA1	SPDEF	ENSCAFP00000030036	ENSCAFP00000001756	Chloride channel accessory 1.	SAM pointed domain containing ETS transcription factor.	0.595
FOXA1	FOXA2	ENSCAFP00000020254	ENSCAFP00000007716	Forkhead box A1.	Forkhead box A2.	0.443
FOXA1	FOXA3	ENSCAFP00000020254	ENSCAFP00000006480	Forkhead box A1.	Forkhead box A3.	0.627
FOXA1	GATA1	ENSCAFP00000020254	ENSCAFP00000022898	Forkhead box A1.	GATA binding protein 1.	0.444
FOXA1	GATA4	ENSCAFP00000020254	ENSCAFP00000038219	Forkhead box A1.	Transcription factor GATA-4; Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes [...]	0.675
FOXA1	HHEX	ENSCAFP00000020254	ENSCAFP00000011144	Forkhead box A1.	Hematopoietically expressed homeobox.	0.503
FOXA1	SPDEF	ENSCAFP00000020254	ENSCAFP00000001756	Forkhead box A1.	SAM pointed domain containing ETS transcription factor.	0.402
FOXA2	FOXA1	ENSCAFP00000007716	ENSCAFP00000020254	Forkhead box A2.	Forkhead box A1.	0.443
FOXA2	FOXA3	ENSCAFP00000007716	ENSCAFP00000006480	Forkhead box A2.	Forkhead box A3.	0.513
FOXA2	GATA4	ENSCAFP00000007716	ENSCAFP00000038219	Forkhead box A2.	Transcription factor GATA-4; Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes [...]	0.818
FOXA2	HHEX	ENSCAFP00000007716	ENSCAFP00000011144	Forkhead box A2.	Hematopoietically expressed homeobox.	0.742
FOXA2	SPDEF	ENSCAFP00000007716	ENSCAFP00000001756	Forkhead box A2.	SAM pointed domain containing ETS transcription factor.	0.565
FOXA3	CLCA1	ENSCAFP00000006480	ENSCAFP00000030036	Forkhead box A3.	Chloride channel accessory 1.	0.522
FOXA3	FOXA1	ENSCAFP00000006480	ENSCAFP00000020254	Forkhead box A3.	Forkhead box A1.	0.627
FOXA3	FOXA2	ENSCAFP00000006480	ENSCAFP00000007716	Forkhead box A3.	Forkhead box A2.	0.513
FOXA3	GATA1	ENSCAFP00000006480	ENSCAFP00000022898	Forkhead box A3.	GATA binding protein 1.	0.518
FOXA3	GATA4	ENSCAFP00000006480	ENSCAFP00000038219	Forkhead box A3.	Transcription factor GATA-4; Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes [...]	0.576
FOXA3	HHEX	ENSCAFP00000006480	ENSCAFP00000011144	Forkhead box A3.	Hematopoietically expressed homeobox.	0.549
FOXA3	LGALS2	ENSCAFP00000006480	ENSCAFP00000052081	Forkhead box A3.	Galectin.	0.555