STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABI1Abl interactor 1. (508 aa)    
Predicted Functional Partners:
NCKAP1
NCK associated protein 1.
   
 0.999
WASF3
WASP family member 3.
   
 0.998
WASF2
WASP family member 2.
   
 0.998
WASF1
WASP family member 1.
   
 0.997
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 0.996
CYFIP2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 0.996
BRK1
BRICK1 subunit of SCAR/WAVE actin nucleating complex.
    
 0.992
NCKAP1L
NCK associated protein 1 like.
   
 0.989
ABL1
Tyrosine-protein kinase.
    
 0.987
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.981
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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