NOX4 protein (Canis lupus familiaris) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

NOX4

NADPH oxidase 4. (323 aa)

Predicted Functional Partners:

CYBA

0.999

NCF2

0.944

NOXO1

0.906

NOX5

0.848

NOX1

0.818

POLDIP2

0.725

NOXA1

0.708

NOX3

0.704

DUOX1

0.683

SMAD3

0.649

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYBA	DUOX1	ENSCAFP00000054508	ENSCAFP00000020209	Cytochrome b-245 alpha chain.	Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.	0.830
CYBA	NCF2	ENSCAFP00000054508	ENSCAFP00000054948	Cytochrome b-245 alpha chain.	Neutrophil cytosolic factor 2.	0.999
CYBA	NOX1	ENSCAFP00000054508	ENSCAFP00000025906	Cytochrome b-245 alpha chain.	NADPH oxidase 1.	0.999
CYBA	NOX3	ENSCAFP00000054508	ENSCAFP00000000844	Cytochrome b-245 alpha chain.	Predicted NADPH oxidase-3.	0.976
CYBA	NOX4	ENSCAFP00000054508	ENSCAFP00000006503	Cytochrome b-245 alpha chain.	NADPH oxidase 4.	0.999
CYBA	NOX5	ENSCAFP00000054508	ENSCAFP00000061876	Cytochrome b-245 alpha chain.	NADPH oxidase 5.	0.793
CYBA	NOXA1	ENSCAFP00000054508	ENSCAFP00000028742	Cytochrome b-245 alpha chain.	NADPH oxidase activator 1.	0.837
CYBA	NOXO1	ENSCAFP00000054508	ENSCAFP00000028783	Cytochrome b-245 alpha chain.	NADPH oxidase organizer 1.	0.999
CYBA	POLDIP2	ENSCAFP00000054508	ENSCAFP00000027538	Cytochrome b-245 alpha chain.	DNA polymerase delta interacting protein 2.	0.678
DUOX1	CYBA	ENSCAFP00000020209	ENSCAFP00000054508	Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.	Cytochrome b-245 alpha chain.	0.830
DUOX1	NCF2	ENSCAFP00000020209	ENSCAFP00000054948	Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.	Neutrophil cytosolic factor 2.	0.687
DUOX1	NOX1	ENSCAFP00000020209	ENSCAFP00000025906	Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.	NADPH oxidase 1.	0.635
DUOX1	NOX3	ENSCAFP00000020209	ENSCAFP00000000844	Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.	Predicted NADPH oxidase-3.	0.490
DUOX1	NOX4	ENSCAFP00000020209	ENSCAFP00000006503	Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.	NADPH oxidase 4.	0.683
DUOX1	NOX5	ENSCAFP00000020209	ENSCAFP00000061876	Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.	NADPH oxidase 5.	0.751
DUOX1	NOXA1	ENSCAFP00000020209	ENSCAFP00000028742	Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.	NADPH oxidase activator 1.	0.575
DUOX1	NOXO1	ENSCAFP00000020209	ENSCAFP00000028783	Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.	NADPH oxidase organizer 1.	0.747
DUOX1	POLDIP2	ENSCAFP00000020209	ENSCAFP00000027538	Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.	DNA polymerase delta interacting protein 2.	0.441
NCF2	CYBA	ENSCAFP00000054948	ENSCAFP00000054508	Neutrophil cytosolic factor 2.	Cytochrome b-245 alpha chain.	0.999
NCF2	DUOX1	ENSCAFP00000054948	ENSCAFP00000020209	Neutrophil cytosolic factor 2.	Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.	0.687