STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM135Transmembrane protein 135. (458 aa)    
Predicted Functional Partners:
PXMP4
Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family.
      
 0.773
CCDC170
Coiled-coil domain containing 170.
      
 0.663
GPATCH1
G-patch domain containing 1.
      
 0.634
TIMM17A
Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
      
 0.579
SEPTIN5
Septin 5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
      
 0.572
MAN2A1
Alpha-mannosidase.
      
 0.544
FAM167A
Family with sequence similarity 167 member A.
      
 0.544
TMEM115
Transmembrane protein 115.
      
 0.542
ACBD5
Acyl-CoA-binding domain-containing protein 5; Binds medium- and long-chain acyl-CoA esters.
   
 
 0.531
SLC16A7
Solute carrier family 16 member 7.
      
 0.525
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.