STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CHCHD4Coiled-coil-helix-coiled-coil-helix domain containing 4. (140 aa)    
Predicted Functional Partners:
TIMM10
Translocase of inner mitochondrial membrane 10.
   
 
 0.934
AIFM1
Apoptosis inducing factor mitochondria associated 1.
    
 
 0.904
GFER
Sulfhydryl oxidase.
    
 
 0.900
COX17
Cytochrome c oxidase copper chaperone; Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2).
   
 
 0.899
NDUFS5
NADH:ubiquinone oxidoreductase subunit S5.
    
 
 0.845
ATP23
Mitochondrial inner membrane protease ATP23; Belongs to the peptidase M76 family.
    
 
 0.744
NFE2L1
Nuclear factor, erythroid 2 like 1.
      
 0.738
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.716
TIMM8A
Translocase of inner mitochondrial membrane 8A; Belongs to the small Tim family.
   
 
 0.710
ENSCAFP00000064105
zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family.
   
 
 0.710
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.