STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHCHD4Coiled-coil-helix-coiled-coil-helix domain containing 4. (140 aa)    
Predicted Functional Partners:
COX17
Cytochrome c oxidase copper chaperone; Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2).
   
 
 0.957
GFER
Sulfhydryl oxidase.
   
 
 0.910
TIMM10
Translocase of inner mitochondrial membrane 10.
   
 
 0.827
ATP23
Mitochondrial inner membrane protease ATP23; Belongs to the peptidase M76 family.
   
 
 0.755
TIMM10B
Translocase of inner mitochondrial membrane 10B.
   
 
 0.683
TIMM8A
Translocase of inner mitochondrial membrane 8A; Belongs to the small Tim family.
   
 
 0.635
ENSCAFP00000064105
zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family.
   
 
 0.622
TIMM9
Translocase of inner mitochondrial membrane 9.
   
 
 0.608
TIMM9-2
Translocase of inner mitochondrial membrane 9.
   
 
 0.602
ENSCAFP00000062192
Uncharacterized protein.
   
 
 0.602
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.