STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF282Zinc finger protein 282. (641 aa)    
Predicted Functional Partners:
ZNF133
Zinc finger protein 133.
   
  
0.654
CALCOCO1
Calcium binding and coiled-coil domain 1.
   
 
 0.535
ZNF79
Zinc finger protein 79.
   
  
0.514
CXXC1
CXXC finger protein 1.
   
  
 0.503
J9P6F4_CANLF
KRAB domain-containing protein.
   
 
0.482
ZNF777
Zinc finger protein 777.
  
 
0.469
YWHAZ
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
   
 
 0.468
YWHAZ-2
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
   
 
 0.468
SPPL2B
Signal peptide peptidase like 2B.
      
 0.449
HORMAD1
HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]
    
 
 0.428
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.