ITM2B protein (Canis lupus familiaris) - STRING interaction network

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Score

ITM2B

Integral membrane protein 2B. (210 aa)

Predicted Functional Partners:

APP

0.850

LOC607874

0.765

ENSCAFP00000066092

0.765

TMEM59

0.647

APLP2

0.646

SCAMP1

0.608

TMEM59L

0.583

JAGN1

0.581

GNB1L

0.579

CAB39L

0.572

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APLP2	APP	ENSCAFP00000014894	ENSCAFP00000012583	Amyloid beta precursor like protein 2.	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.971
APLP2	ITM2B	ENSCAFP00000014894	ENSCAFP00000006631	Amyloid beta precursor like protein 2.	Integral membrane protein 2B.	0.646
APP	APLP2	ENSCAFP00000012583	ENSCAFP00000014894	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Amyloid beta precursor like protein 2.	0.971
APP	ENSCAFP00000066092	ENSCAFP00000012583	ENSCAFP00000066092	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Cystatin domain-containing protein; Belongs to the cystatin family.	0.460
APP	ITM2B	ENSCAFP00000012583	ENSCAFP00000006631	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Integral membrane protein 2B.	0.850
APP	LOC607874	ENSCAFP00000012583	ENSCAFP00000036304	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Cystatin domain-containing protein.	0.548
CAB39L	ITM2B	ENSCAFP00000064713	ENSCAFP00000006631	Calcium binding protein 39 like.	Integral membrane protein 2B.	0.572
ENSCAFP00000066092	APP	ENSCAFP00000066092	ENSCAFP00000012583	Cystatin domain-containing protein; Belongs to the cystatin family.	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.460
ENSCAFP00000066092	ITM2B	ENSCAFP00000066092	ENSCAFP00000006631	Cystatin domain-containing protein; Belongs to the cystatin family.	Integral membrane protein 2B.	0.765
GNB1L	ITM2B	ENSCAFP00000021396	ENSCAFP00000006631	G protein subunit beta 1 like.	Integral membrane protein 2B.	0.579
GNB1L	JAGN1	ENSCAFP00000021396	ENSCAFP00000037613	G protein subunit beta 1 like.	Jagunal homolog 1.	0.801
ITM2B	APLP2	ENSCAFP00000006631	ENSCAFP00000014894	Integral membrane protein 2B.	Amyloid beta precursor like protein 2.	0.646
ITM2B	APP	ENSCAFP00000006631	ENSCAFP00000012583	Integral membrane protein 2B.	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.850
ITM2B	CAB39L	ENSCAFP00000006631	ENSCAFP00000064713	Integral membrane protein 2B.	Calcium binding protein 39 like.	0.572
ITM2B	ENSCAFP00000066092	ENSCAFP00000006631	ENSCAFP00000066092	Integral membrane protein 2B.	Cystatin domain-containing protein; Belongs to the cystatin family.	0.765
ITM2B	GNB1L	ENSCAFP00000006631	ENSCAFP00000021396	Integral membrane protein 2B.	G protein subunit beta 1 like.	0.579
ITM2B	JAGN1	ENSCAFP00000006631	ENSCAFP00000037613	Integral membrane protein 2B.	Jagunal homolog 1.	0.581
ITM2B	LOC607874	ENSCAFP00000006631	ENSCAFP00000036304	Integral membrane protein 2B.	Cystatin domain-containing protein.	0.765
ITM2B	SCAMP1	ENSCAFP00000006631	ENSCAFP00000052271	Integral membrane protein 2B.	Secretory carrier-associated membrane protein.	0.608
ITM2B	TMEM59	ENSCAFP00000006631	ENSCAFP00000065352	Integral membrane protein 2B.	Transmembrane protein 59.	0.647