STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRCH1Leucine rich repeats and calponin homology domain containing 1. (735 aa)    
Predicted Functional Partners:
DOCK8
Dedicator of cytokinesis 8; Belongs to the DOCK family.
   
 
 0.940
LRCH3
Leucine rich repeats and calponin homology domain containing 3.
   
   0.929
DOCK6
Dedicator of cytokinesis 6; Belongs to the DOCK family.
   
 
 0.790
DOCK7
Dedicator of cytokinesis 7; Belongs to the DOCK family.
   
 
 0.767
CTIF
Cap binding complex dependent translation initiation factor.
      
 0.742
PPARGC1A
PPARG coactivator 1 alpha.
    
 
 0.719
RTN1
Reticulon.
    
 
 0.702
TMEM64
Transmembrane protein 64.
      
 0.694
TTC34
Tetratricopeptide repeat domain 34.
      
 0.692
FUBP3
Far upstream element binding protein 3.
      
 0.673
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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