STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRCH1Leucine rich repeats and calponin homology domain containing 1. (735 aa)    
Predicted Functional Partners:
CTIF
Cap binding complex dependent translation initiation factor.
      
 0.930
DOCK8
Dedicator of cytokinesis 8; Belongs to the DOCK family.
   
 
 0.787
TMEM64
Transmembrane protein 64.
   
  
 0.783
FBXO8
F-box protein 8.
   
  
 0.677
FUBP3
Far upstream element binding protein 3.
   
  
 0.674
KPNA3
Importin subunit alpha; Functions in nuclear protein import.
   
 
 0.668
DOCK6
Dedicator of cytokinesis 6; Belongs to the DOCK family.
   
 
 0.659
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1.
   
  
 0.656
RORA
RAR related orphan receptor A.
   
  
 0.652
ADGRL2
Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.
   
   0.636
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.