IWS1 protein (Canis lupus familiaris) - STRING interaction network

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Score

IWS1

Interacts with SUPT6H, CTD assembly factor 1. (866 aa)

Predicted Functional Partners:

SUPT6H

0.995

SUPT5H

0.929

POLR2A

0.909

SUPT16H

0.907

TCEA1

0.895

POLR2C

0.885

POLR2B

0.882

CTR9

0.867

SSRP1

0.854

LEO1

0.854

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTR9	IWS1	ENSCAFP00000011354	ENSCAFP00000006679	CTR9 homolog, Paf1/RNA polymerase II complex component.	Interacts with SUPT6H, CTD assembly factor 1.	0.867
CTR9	LEO1	ENSCAFP00000011354	ENSCAFP00000044474	CTR9 homolog, Paf1/RNA polymerase II complex component.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.999
CTR9	POLR2A	ENSCAFP00000011354	ENSCAFP00000037353	CTR9 homolog, Paf1/RNA polymerase II complex component.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.958
CTR9	POLR2B	ENSCAFP00000011354	ENSCAFP00000003370	CTR9 homolog, Paf1/RNA polymerase II complex component.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.918
CTR9	POLR2C	ENSCAFP00000011354	ENSCAFP00000012825	CTR9 homolog, Paf1/RNA polymerase II complex component.	RNA polymerase II subunit C.	0.936
CTR9	SSRP1	ENSCAFP00000011354	ENSCAFP00000011769	CTR9 homolog, Paf1/RNA polymerase II complex component.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.940
CTR9	SUPT16H	ENSCAFP00000011354	ENSCAFP00000008366	CTR9 homolog, Paf1/RNA polymerase II complex component.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.979
CTR9	SUPT5H	ENSCAFP00000011354	ENSCAFP00000062824	CTR9 homolog, Paf1/RNA polymerase II complex component.	Transcription elongation factor SPT5.	0.957
CTR9	SUPT6H	ENSCAFP00000011354	ENSCAFP00000027693	CTR9 homolog, Paf1/RNA polymerase II complex component.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.944
CTR9	TCEA1	ENSCAFP00000011354	ENSCAFP00000052821	CTR9 homolog, Paf1/RNA polymerase II complex component.	Transcription elongation factor A1.	0.735
IWS1	CTR9	ENSCAFP00000006679	ENSCAFP00000011354	Interacts with SUPT6H, CTD assembly factor 1.	CTR9 homolog, Paf1/RNA polymerase II complex component.	0.867
IWS1	LEO1	ENSCAFP00000006679	ENSCAFP00000044474	Interacts with SUPT6H, CTD assembly factor 1.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.854
IWS1	POLR2A	ENSCAFP00000006679	ENSCAFP00000037353	Interacts with SUPT6H, CTD assembly factor 1.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.909
IWS1	POLR2B	ENSCAFP00000006679	ENSCAFP00000003370	Interacts with SUPT6H, CTD assembly factor 1.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.882
IWS1	POLR2C	ENSCAFP00000006679	ENSCAFP00000012825	Interacts with SUPT6H, CTD assembly factor 1.	RNA polymerase II subunit C.	0.885
IWS1	SSRP1	ENSCAFP00000006679	ENSCAFP00000011769	Interacts with SUPT6H, CTD assembly factor 1.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.854
IWS1	SUPT16H	ENSCAFP00000006679	ENSCAFP00000008366	Interacts with SUPT6H, CTD assembly factor 1.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.907
IWS1	SUPT5H	ENSCAFP00000006679	ENSCAFP00000062824	Interacts with SUPT6H, CTD assembly factor 1.	Transcription elongation factor SPT5.	0.929
IWS1	SUPT6H	ENSCAFP00000006679	ENSCAFP00000027693	Interacts with SUPT6H, CTD assembly factor 1.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.995
IWS1	TCEA1	ENSCAFP00000006679	ENSCAFP00000052821	Interacts with SUPT6H, CTD assembly factor 1.	Transcription elongation factor A1.	0.895