STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM104AFamily with sequence similarity 104 member A. (352 aa)    
Predicted Functional Partners:
CDC42SE1
CDC42 small effector 1.
   
  
 0.721
CDC42BPB
CDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
      
 0.701
BAIAP2L1
BAI1 associated protein 2 like 1.
   
  
 0.684
CDC42SE2
CDC42 small effector 2.
      
 0.681
ARHGEF3
Rho guanine nucleotide exchange factor 3.
      
 0.681
SEPTIN8
Septin 8; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
   
 
 0.668
SEPTIN7
Septin 7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
   
 
 0.667
SEPTIN3
Septin 3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
   
 
 0.653
SEPTIN11
Septin 11; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
    
 
 0.649
TLR9
Twinfilin actin binding protein 2.
      
 0.643
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.