SIAH3 protein (Canis lupus familiaris) - STRING interaction network

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SIAH3

E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (266 aa)

Predicted Functional Partners:

CACYBP

0.711

TOMM7

0.643

PINK1

0.600

LRCH1

0.591

MORN1

0.583

TTC34

0.518

LRRC63

0.506

SLC52A1

0.469

GMDS

0.468

TBL1XR1

0.461

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACYBP	SIAH3	ENSCAFP00000040621	ENSCAFP00000006741	Calcyclin binding protein.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.711
CACYBP	TBL1XR1	ENSCAFP00000040621	ENSCAFP00000022867	Calcyclin binding protein.	Transducin beta like 1 X-linked receptor 1.	0.585
GMDS	SIAH3	ENSCAFP00000062974	ENSCAFP00000006741	GDP-mannose 4,6-dehydratase.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.468
LRCH1	MORN1	ENSCAFP00000006677	ENSCAFP00000028664	Leucine rich repeats and calponin homology domain containing 1.	MORN repeat containing 1.	0.413
LRCH1	SIAH3	ENSCAFP00000006677	ENSCAFP00000006741	Leucine rich repeats and calponin homology domain containing 1.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.591
LRCH1	TTC34	ENSCAFP00000006677	ENSCAFP00000028794	Leucine rich repeats and calponin homology domain containing 1.	Tetratricopeptide repeat domain 34.	0.692
LRRC63	MORN1	ENSCAFP00000039213	ENSCAFP00000028664	Leucine rich repeat containing 63.	MORN repeat containing 1.	0.525
LRRC63	SIAH3	ENSCAFP00000039213	ENSCAFP00000006741	Leucine rich repeat containing 63.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.506
LRRC63	TTC34	ENSCAFP00000039213	ENSCAFP00000028794	Leucine rich repeat containing 63.	Tetratricopeptide repeat domain 34.	0.525
MORN1	LRCH1	ENSCAFP00000028664	ENSCAFP00000006677	MORN repeat containing 1.	Leucine rich repeats and calponin homology domain containing 1.	0.413
MORN1	LRRC63	ENSCAFP00000028664	ENSCAFP00000039213	MORN repeat containing 1.	Leucine rich repeat containing 63.	0.525
MORN1	SIAH3	ENSCAFP00000028664	ENSCAFP00000006741	MORN repeat containing 1.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.583
MORN1	TTC34	ENSCAFP00000028664	ENSCAFP00000028794	MORN repeat containing 1.	Tetratricopeptide repeat domain 34.	0.494
PINK1	SIAH3	ENSCAFP00000057576	ENSCAFP00000006741	PTEN induced kinase 1.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.600
PINK1	TOMM7	ENSCAFP00000057576	ENSCAFP00000037774	PTEN induced kinase 1.	Translocase of outer mitochondrial membrane 7.	0.979
SIAH3	CACYBP	ENSCAFP00000006741	ENSCAFP00000040621	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Calcyclin binding protein.	0.711
SIAH3	GMDS	ENSCAFP00000006741	ENSCAFP00000062974	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	GDP-mannose 4,6-dehydratase.	0.468
SIAH3	LRCH1	ENSCAFP00000006741	ENSCAFP00000006677	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Leucine rich repeats and calponin homology domain containing 1.	0.591
SIAH3	LRRC63	ENSCAFP00000006741	ENSCAFP00000039213	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Leucine rich repeat containing 63.	0.506
SIAH3	MORN1	ENSCAFP00000006741	ENSCAFP00000028664	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	MORN repeat containing 1.	0.583

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