STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MARK4Non-specific serine/threonine protein kinase. (734 aa)    
Predicted Functional Partners:
CEP97
Centrosomal protein 97.
      
 0.739
SVBP
Small vasohibin binding protein.
      
 0.677
USP9X
UCH domain-containing protein.
    
 
 0.603
MAP4
Microtubule-associated protein.
    
 
 0.577
MKKS
McKusick-Kaufman syndrome.
    
 
 0.562
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.
    
 
 0.532
AIMP1
Aminoacyl tRNA synthetase complex interacting multifunctional protein 1.
    
 
 0.527
VASH2
Vasohibin 2.
      
 0.515
TTL
Tubulin tyrosine ligase.
      
 0.509
RAB11A
Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...]
    
  0.506
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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