STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VIMIF rod domain-containing protein; Belongs to the intermediate filament family. (524 aa)    
Predicted Functional Partners:
ZEB1
Zinc finger E-box binding homeobox 1.
   
  
 0.714
SNAI1
Snail family transcriptional repressor 1.
      
 0.648
TMEFF2
Transmembrane protein with EGF like and two follistatin like domains 2.
   
  
 0.641
SNAI2
Snail family transcriptional repressor 2.
   
  
 0.639
ZEB2
Zinc finger E-box binding homeobox 2.
   
  
 0.585
NES
Nestin; Belongs to the intermediate filament family.
   
 
0.559
GDF15
Growth differentiation factor 15.
   
 
 0.531
CDH1
Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
    
 
 0.528
SELENOS
Selenoprotein S.
   
  
 0.523
CD68
CD68 molecule.
   
  
 0.494
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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