STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (620 aa)    
Predicted Functional Partners:
MAP2K5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
    
 0.983
MAP3K3
Mitogen-activated protein kinase kinase kinase 3.
   
  0.952
PAK1
Non-specific serine/threonine protein kinase.
    
 0.916
PAK2
Non-specific serine/threonine protein kinase.
    
 0.916
MAP2K3
Mitogen-activated protein kinase kinase 3.
    
 0.904
SMYD3
SET and MYND domain containing 3.
    
 
 0.902
MAP2K6
Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
    
 0.898
SRC
Tyrosine-protein kinase.
    
  0.884
MAP3K4
Mitogen-activated protein kinase kinase kinase 4.
   
0.881
MAP2K4
Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.
    
 0.853
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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