STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCTD4Potassium channel tetramerization domain containing 4. (258 aa)    
Predicted Functional Partners:
GIGYF2
GRB10 interacting GYF protein 2.
      
 0.785
LDB2
LIM domain binding 2.
      
 0.697
TULP2
Tubby like protein 2; Belongs to the TUB family.
   
  
 0.683
TF
Transferrin; Belongs to the transferrin family.
      
 0.581
GTF2F2
General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
      
 0.564
FBXL3
F-box and leucine rich repeat protein 3.
      
 0.536
CRISPLD2
Cysteine rich secretory protein LCCL domain containing 2.
   
  
 0.521
WDFY2
WD repeat and FYVE domain containing 2.
    
 
 0.486
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
   
  
 0.486
PCDH7
Protocadherin 7.
   
  
 0.485
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.