STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCTD4Potassium channel tetramerization domain containing 4. (258 aa)    
Predicted Functional Partners:
KCTD20
Potassium channel tetramerization domain containing 20.
      
 0.659
BTBD10
BTB domain containing 10.
      
 0.656
GTF2F2
General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
      
 0.614
GIGYF2
GRB10 interacting GYF protein 2.
      
 0.603
TULP2
Tubby like protein 2; Belongs to the TUB family.
      
 0.567
KCTD3
Potassium channel tetramerization domain containing 3.
    
 
 0.523
KCTD2
Potassium channel tetramerization domain containing 2.
    
 
 0.481
WDFY2
WD repeat and FYVE domain containing 2.
      
 0.466
KCTD10
Potassium channel tetramerization domain containing 10.
    
 
 0.455
KCTD14
Potassium channel tetramerization domain containing 14.
      
 0.454
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.