STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BIN1Bridging integrator 1. (788 aa)    
Predicted Functional Partners:
AMPH
Amphiphysin.
    
 
0.966
CYP26A1
Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.
  
 
 
0.922
LRAT
Lecithin retinol acyltransferase.
   
 0.908
RDH12
Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.905
RDH11
Retinol dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.905
RDH8
Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.904
ADH5
S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
   
 
  0.903
ADH4
Alcohol dehydrogenase 4 (class II), pi polypeptide.
   
 
  0.903
LOC100856533
PKS_ER domain-containing protein.
   
 
  0.903
HSD17B6
Hydroxysteroid 17-beta dehydrogenase 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
  0.901
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.